Contact
Positions
Adjunct Assistant Professor
- Organization:
- West Virginia University School of Medicine
- Department:
- Microbiology, Immunology & Cell Biology
- Classification:
- Adjunct Faculty
- Organization:
- West Virginia University School of Public Health
- Department:
- Occupational and Environmental Health Sciences
- Classification:
- Adjunct Faculty
Publications
1. Sisler JD, Pirela S, Friend S, Farcas MT, Schwegler-Berry DE, Shvedova AA, Castranova V,
Demokritou P, Yong Qian*. 2015
Small airway epithelial cells exposure to printer emitted nanoparticles induces cellular effects on
human microvascular endothelial cells in an alveolar-capillary co-culture model.
Nanotoxicology. 9(6):769-79.*Corresponding author
2. Talkington BN, Dong C, Zhao X, Dymacek J, Porter DW, Wolfarth M, Castranova V, Yong
Qian*, Guo NL. 2015.
Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies.
Toxicology. 3;328:66-74. *Corresponding author
3. Dymacek J, Talkington BN, Porter DW, Wolfarth M, Castranova V, Yong Qian, Guo NL. 2015.
mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung
inflammatory and fibrotic pathologies in mice.
Toxicol Sci. 144(1):51-64.
4. Mihalchik AL, Ding W, Porter DW, McLoughlin CE, Schwegler-Berry DE, Sisler JD, Stefaniak A,
Talkington BN, Tsuruoka S, Endo M, Castranova V, Yong Qian*. 2015
Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled
carbon nanotubes on human small airway epithelial cells .
Toxicology. 333:25-36. *Corresponding author
5. Talkington BN, Dong C, Sargent LM, Porter DW, Raese R, McKinney W, Chen BT, Battelli L,
Lowry D, Reynolds SH, Castranova V, Yong Qian*and Guo NL 2016
mRNAs and miRNAs in whole blood associated with MWCNT-induced lung hyperplasia, fibrosis,
and bronchiolo-alveolar adenoma and adenocarcinoma following inhalation exposure in mice.
*Corresponding author
Journal of Applied Toxicology. 36(1):161-74.
6. Pirela SV, Miousse IR, Lu X, Castranova V, Thomas T, Yong Qian, Bello D, Kobzik L,
Koturbash L, Demokritou P. 2016.
Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine
Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive
in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts.
Environmental Health Perspectives. 124(2):210-9.
7. Pirela SV, Lu X, Miousse L, Sisler JD, Yong Qian, Guo, N, Koturbash I, Castranova V, Thomas
T, Godleski J, and Demokritou P. 2016
Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model:
A case study of toxicological implications from nanomaterials released during consumer use
NanoImpact. 1(2016):1-8
8. Sisler JD, Pirela SV, Shaffer J, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V,
Demokritou P, and Yong Qian* 2016
Toxicological Assessment of CoO and La2O3 Metal Oxide Nanoparticles in Human Small Airway
Epithelial Cells.
Toxicological Sciences 150(2):418-28. *Corresponding author
9. Snyder-Talkington BN, Dong C, Porter DW, Ducatman B, Wolfarth MG, Andrew ME, Battelli L,
Raese R, Castranova V, GuoNL, and Yong Qian* 2016
Multi-walled carbon nanotube-induced pulmonary inflammatory and fibrotic responses and
genomic changes following aspiration exposure in mice: a 1-year post-exposure study.
Journal of Toxicology and Environmental Health. 2016 79(8):352-66 *Corresponding author
10. Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia Z, Wang X, Shaffer J, Orandle M,
Mihalchik A, Battelli, Chen T, Wolfarth MG, Andrew ME, Schwegler-Berry D, Porter DW,
Castranova V, Nel A, and Yong Qian* 2016
Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during
aerosolized inhalation in mice.
Particle and Fibra Toxicology 13(1):42. *Corresponding author
11. Mercer RR, Scabilloni JF, Wang L, Battelli LA, Antonini JM, Roberts JR, Yong Qian, Sisler
JD, Castranova V, Porter DW, Hubbs AF. 2018
The fate of inhaled nanoparticles: detection and measurement by enhanced darkfield microscopy.
Toxicologic Pathology. 46(1):28-46
12. Zhao J, Zhang Y, Sisler SD, Shaffer J, Leonard SS, Morris AM, Yong Qian, Bello D,
Demokritou D. 2018
Assessment of reactive oxygen species generated by electronic cigarettes using acellular and
cellular approaches.
Journal of Hazardous Materials. 344:549-57
13. Sisler SD, Qi Q, McKinney W, Shaffer J, Andrew M, Lee L, Thomas T, Castranova V, Mercer
RR, and Yong Qian*. 2018
Physical Chemical Properties and Cell Toxicity of Sanding Copper-Treated Lumber
Journal of Occupational and Environmental Hygiene.15(4):311-321
*Corresponding Author.
14. Chalbot MG, Pirela SV, Schifman L, Kasaraneni V, Oyanedel-Craver V, Bello D, Castranova V,
Yong Qian, Thomas T, Kavouras IG, Demokritou P. 2017
Synergistic effects of engineered nanoparticles and organics released from laser printers using
nano-enabled toners: potential health implications from exposures to the emitted organic aerosol.
Environmental Science: Nano. 4(11):2144-2156
15. Sisler SD, Shaffer J, Soo J, Lebouf R, Harper M, Yong Qian* and Lee T. 2018
In vitro toxicological evaluation of surgical smoke from human tissue.
Journal of Occupational and Environmental Hygiene. 13:12. *Corresponding
Author.
16. Dymacek J, Snyder-Talkington B, Dong C, Singh S, Rease R, Porter D, Ducatman B, Wolfarth M,
Andrew M, Battelli L, Castranova V, Yong Qian, Guo N. 2018.
Similar and differential canonical pathways and biological processes associated with multi-walled
carbon nanotube and asbestos-induced pulmonary fibrosis: a 1-year post-exposure study .
Int J Toxicol. 37(4)276-284
17. Guo NL, Dowlati A, Beer DG, Raese RA, Dong C, Chen G, Sfhffer J, Singh S, Bokhary U, Liu L,
Howington J and Yong Qian. 2018
A predictive 7-gene assay and prognostic protein biomarkers for non-small lung cell lung cancer
EBioMedicine. 32:102-110
18. Stefaniak AB, Bowers LN, Knepp AK, Virji MA, Birch ME, Ham JE, Wells JR, Qi C, Schwegler-
Berry D, Friend S, Johnson AR, Martin JB, Yong Qian, LeBouf RF, Hammond D. 2018
3-dimensional printing with nano-enabled filaments releases polymer particles containing carbon
nanotubes into air
Indoor Air. 28(6):840-851
19. Sisler j, Mandler WK, Shaffer J, Lee T, McKinney W, Battelli L, Orandle M, Thomas T,
Castranova V, Qi C, Porter D, Andrew m, Fedan J, Mercer R, and Yong Qian*. 2019
Toxicological Assessment of Dust from Sanding Micronized Copper-Treated Lumber In Vivo.
Journal of Hazardous Materials. 373:630-639 *Corresponding Author.
20. Kang S, Liang H, Yong Qian and Qi C. 2019
The composition of emissions from sawing corian®, a solid surface composite material.
Annals of Work Exposures and Health. 63(4): 480-483
21. Mandler WK, Qi C, Orandle MS, Sarkisian K, Mercer RR, Stefaniak AB, Knepp AK, Bowers LN,
Battelli LA, Shaffer J, Friend SA, Yong Qian*, and Sisler JD. 2019
Mouse pulmonary response to dust from sawing Corian®, a solid-surface composite material.
Journal of Toxicology and Environmental Health, Part A. 82(11):645-663. *Corresponding
Author.
22. Snyder-Talkington BN, Dong C, Castranova V, Yong Qian and Guo NL. 2019
Differential gene expression in human small airway epithelial cells grown in monoculture versus
coculture with human microvascular endothelial cells following multiwalled carbon nanotube
exposure.
Toxicology Reports 6:482-488
23. Snyder-Talkington BN, Song C, Singh S, Raese R, Yong Qian, Porter DW, Wolfarth MG and Guo
NL. 2019
Multi-walled Carbon Nanotube-Induced Gene Expression Biomarkers for Medical and
Occupational Surveillance.
International Journal of Molecular Sciences. 20(11):2635
24. Farcas MT, Stefaniak AB, Knef A, Bowers L, Mandler WK, Jackson S, Stueckle TA, Sisler JD,
Friend SA, Qi C, Hammond D, Kashon M, Thomas TA, Matheson J. and Yong Qian*. 2019
Three-dimensional (3-D) printer emission-induced cell toxicity.
Toxicology Letters 25;317:1-12 *Corresponding Author.
25. Guo NL, Pirela S, Farcas M, Poh TY, Chotirmall Sh, Tham Wk, Adav SS, Wang Y, Ng KW, Ye
Q, Thomas T, Yong Qian, and Demokritou P. 2019
Integrated transcriptomics, metabolomics, and lipidomics profiling in rat lung, blood, and serum
for assessment of laser printer-emitted particles inhalation exposure-induced disease risk.
Internal Journal of Molecular Sciences. 20(24):6348
26. Carll AP, Salatini R, Pirela SV, Wang Y, Xie Z, Lorkiewicz P, Naeem N, Yong Qian, Castranova
V, Godleski JJ, and Deomokritou P. 2020
Inhalation of Printer-Emitted Particles Impairs Cardiac Conduction, Hemodynamics, and
Autonomic Regulation and Induces Arrhythmia in Conscious Rats.
Particle and Fibra Toxicology. 2020 17(1):7
27. Mandler WK, Kang S, Farcas M, QI C, Sherri AF, and Yong Qian*. 2020
In vitro toxicity assessment of respirable solid surface composite sawing particles
*Corresponding Author.
Toxicol Ind Health. 36(4):250-262
28. Farcas MT, McKinney W, Qi C, Mandler WK, Battelli L, Friend SA, Stefaniak AB, Jackson M,
Orandle M, Winn A, Kashon M, LeBouf RF, Hammond DR, Burns D, Ranpara A, Thomas TA,
Matheson J, Yong Qian* 2020 *Corresponding Author.
Pulmonary and systemic toxicity in rats following inhalation exposure of 3-D printer emissions
from acrylonitrile butadiene styrene (ABS) filament.
Inhalation Toxicology . 32(11-12):403-418
29. Kang S, Liang H, Yong Qian, and Qi C. 2021 The Composition of Emissions from Sanding
Corian® with Different Sandpapers.
Aerosol and Air Quality Research. 21(2):200377
Additional Info
Research Projects (ongoing)
- pulmonary and autoimmune responses to aerosolized emissions from 3-D printers
- toxicological assessment of emission from fabricating engineered stone countertop
Research Interests
Research Projects (ongoing)
- pulmonary and autoimmune responses to aerosolized emissions from 3-D printers
- toxicological assessment of emission from fabricating engineered stone countertop