Donald Beezhold, PhD

Adjunct Professor

Organization:

West Virginia University School of Medicine

Department:

Microbiology, Immunology & Cell Biology

Classification:

Adjunct Faculty

Selected Peer-Reviewed Publications (Selected From >150 Articles)
 
Gudewicz PW, Molnar J, Lai MZ, Beezhold DH, Siefring GE, Credo RB, Lorand L. Fibronectin mediated uptake of gelatin-coated latex particles by peritoneal macrophages.  J Cell Biol., 84:427-443, 1980.
 
Beezhold DH, Leftwich JL, Hall RE. P48 induces TNF and IL-1 secretion by human monocytes. J. Immunol., 143:3217-3221, 1989.
 
Beezhold DH, Chang N-S, Kostyal DA, Sussman, G.  Identification of a 46 kilodalton latex protein allergen in healthcare workers.  Clin Exp. Immun. 98:408-413, 1994.
 
Sussman GL, Beezhold DH. Allergy to latex rubber. Annals Internal Medicine 122: 43-46, 1995.
 
Beezhold DH, Sussman GL, Liss G, Chang N-S. Latex allergy can induce clinical reactions to specific foods.  Clin and Exp Allergy 26: 416-422, 1996.
 
Beezhold DH, Pugh B, Liss G, Sussman GL. Correlation of protein levels with skin prick reactions in latex allergic patients.  J Allergy Clin Immunol 98: 1097-1102, 1996.

Beezhold DH, Hickey VL, Sussman GL. Mutational analysis of the IgE epitopes in the latex allergen Hev b 5. J Allergy Clin Immunol. 107:1069-76, 2001.
 
Beezhold D, Hickey V, Kostyal D, Puhl H, Sussman G. Lipid transfer protein from Hevea brasiliensis (Hev b 12), a cross-reactive latex protein. Ann Allergy Asthma Immunol. 90: 439-445, 2003.
 
Beezhold D, Hickey V Sutherland M, O’Hehir R. The latex allergen Hev b 5 is an antigen with repetitive murine B-cell epitopes.  Int Arch Allergy Immunol 134:334-340, 2004.
 
Schmechel D, Simpson JP, Beezhold D, Lewis DM.  The development of species-specific immunodiagnostics for Stachybotrys chartarum: the role of cross-reactivity. J Immunol Methods 309:150-159, 2006.
 
Beezhold D, Green BJ, Blachere FM, Schmechel D, Weissman D, Velickoff D, Hogan MB, and Wilson NW. Prevalence of allergic sensitization to indoor fungi in West Virginia. Allergy and Asthma Proceedings 29 (1): 29-34, 2008.
 
Templeton SP, Buskirk AD, Green BJ, Beezhold DH, Schmechel D.  Animal models of airway fungal exposures and allergic sensitization. Med Mycol 48(2): 217-228, 2009.

Rittenour WR, Hamilton RG, Beezhold DH, Green BJ. Immunologic, Spectrophotometric and Nucleic Acid Based Methods for the Detection and Quantification of Airborne Pollen. J Immunol Methods. 383:47-53, 2012.

Noti JD, Blachere FM, McMillen CM, Lindsley WG, Slaughter D, Beezhold DH. High humidity leads to loss of infectious influenza virus from simulated coughs. PLOS ONE 8(2):e57485, 2013.
 
Nayak, AJ, Green BJ, Sussman G, Berlin N, Lata H, Chandra S, ElSohly MA, Hettick J, Beezhold D,  Characterization of Cannabis Sativa allergens in patients with marijuana hypersensitivity reactions.  Annals of Allergy Asthma and Immunology 111: 32-37, 2013
 
Buskirk, AD, Templeton SP, Nayak AP, Hettick JM, Law BF, Green BJ, Beezhold DH. Pulmonary immune responses to Aspergillus fumigatus in an immunocompetent mouse model of repeated exposures. ImmunoToxicology, 2013; online DOI 10.3109/1547691X.2013.819054.
 
Othumpangat S, Noti J, Blachere F, Beezhold DH. Non-structural-1 A binding protein expression in lung epithelial cells is modulated by miRNA 548an on exposure to influenza A virus. Virology 447: 84-94, 2013.
 
Anderson SE, Beezhold K, Lukomska E, Richardson J, Long C, Anderson K, Franko J, Meade BJ, Beezhold DH. Expression kinetics of miRNAs involved in dermal Toluene 2, 4-diisocyanate sensitization. ImmunoToxicology; online, 2013. DOI: 10.3109/1547691X.2013.835891.

Academic Interests:
Dr. Beezhold is Chief of the Allergy and Clinical Immunology Branch at the National Institute for Occupational Safety and Health. The Allergy and Clinical Immunology Branch (ACIB) conducts basic and applied laboratory research in areas of immunology, allergy, and inflammation relevant to occupational diseases. Current research interests are in the cellular control of the immune response, allergen characterization, and exposure assessment.

Education:
BA Trinity Christian College, Palos Hts, IL, 1977
MS University of Illinois Medical Center, Chicago, IL, 1979
PhD University of Illinois Medical Center, 1981

Positions and Professional Experience:
Instructor of Anatomy, Medical College of Georgia, 1982-1984
Assistant Professor, Department of Anatomy, Medical College of Georgia 1984-1988
Assistant Research Scientist, Director, Lab. of Macrophage Biology, Guthrie Research Institute1988-1992
Associate Research Scientist, Director, Lab. of Macrophage Biology, Guthrie Research Institute, 1992-1996

Director, LEAP Testing Service, Guthrie Research Institute, 1993-2003
Senior Research Scientist, Director, Laboratory of Immunobiology, Guthrie Research Institute, 1996-2003
Toxicologist, HELD, National Institutes for Occupational Safety and Health, Morgantown, WV2003-2004
Chief, Allergy and Clinical Immunology Branch, HELD, NIOSH, Morgantown, WV, 2004-present